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Article

African signatures of recent positive selection in human FOXI1.

BMC evolutionary biology - 1 Sept 2010

Moreno-Estrada Andrés, Aparicio-Prat Estel, Sikora Martin, Engelken Johannes, Ramírez-Soriano Anna, Calafell Francesc, Bosch Elena

Abstract excerpt

BACKGROUND: The human FOXI1 gene codes for a transcription factor involved in the physiology of the inner ear, testis, and kidney. Using three interspecies comparisons, it has been suggested that this may be a gene under human-specific selection. We sought to confirm this finding by using an extended set of orthologous sequences. Additionally, we explored for signals of natural selection within humans by...

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Identifiers

PMID: 20809947
DOI: 10.1186/1471-2148-10-267
PMCID: PMC2939579

Genes

FOXI1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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