Article

Whole genome sequence analyses of Western Central African Pygmy hunter-gatherers reveal a complex demographic history and identify candidate genes under positive natural selection

2015-07-08

Abstract excerpt

African Pygmies practicing a mobile hunter-gatherer lifestyle are phenotypically and genetically diverged from other anatomically modern humans, and they likely experienced strong selective pressures due to their unique lifestyle in the Central African rainforest. To identify genomic targets of adaptation, we sequenced the genomes of four Biaka Pygmies from the Central African Republic and jointly analyzed these d...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ab89ef27-3e07-5e93-a34b-2c1d6b55a9c2
DOI: 10.1101/022194

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Whole genome sequence analyses of Western Central African Pygmy hunter-gatherers reveal a complex demographic history and identify candidate genes under positive natural selectionDOI 10.1101/022194Read

Whole-genome sequence analyses of Western Central African Pygmy hunter-gatherers reveal a complex demographic history and identify candidate genes under positive natural selection.Semantic proximity Read

Adaptive, convergent origins of the pygmy phenotype in African rainforest hunter-gatherers.Semantic proximity Read

Evolutionary history and adaptation from high-coverage whole-genome sequences of diverse African hunter-gatherers.Semantic proximity Read

Patterns of ancestry, signatures of natural selection, and genetic association with stature in Western African pygmies.Semantic proximity Read

African genetic diversity provides novel insights into evolutionary history and local adaptations.Semantic proximity Read

Genomic variation in seven Khoe-San groups reveals adaptation and complex African history.Semantic proximity Read

Origins and genetic diversity of pygmy hunter-gatherers from Western Central Africa.Semantic proximity Read

The demographic history and mutational load of African hunter-gatherers and farmersSemantic proximity Read

An early divergence of KhoeSan ancestors from those of other modern humans is supported by an ABC-based analysis of autosomal resequencing data.Semantic proximity Read

Ancient West African foragers in the context of African population history.Semantic proximity Read

Inferring the demographic history of African farmers and pygmy hunter-gatherers using a multilocus resequencing data set.Semantic proximity Read

Polygenic adaptation and convergent evolution across both growth and cardiac genetic pathways in African and Asian rainforest hunter-gatherersSemantic proximity Read