Article
Adhesive substrates modulate the activation and stimulatory capacity of non-obese diabetic mouse-derived dendritic cells.
Acta biomaterialia - 1 Jan 2011
Acharya Abhinav P, Dolgova Natalia V, Xia Chang Qing, Clare-Salzler Michael J, Keselowsky Benjamin G
Abstract excerpt
It is known that adsorbed adhesive proteins on implanted biomaterials modulate inflammatory responses; however, modulation of dendritic cell (DC) responses upon interaction with adhesive proteins has only begun to be characterized. DCs are specialized antigen-presenting cells that modulate both innate and adaptive immune responses. Previously we have shown that the activation and stimulatory capacity of DCs...
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