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Article

Dendritic cell immune potency on 2D and in 3D collagen matrices

1 Jan 2020

Abstract excerpt

Dendritic cells (DCs) are antigen-presenting cells capable of either activating the immune response or inducing and maintaining immune tolerance. Understanding how biophysical properties affect DC behaviors will provide insight into the biology of a DC and its applications. In this work, we studied how cell culture dimensionality (two-dimensional (2D) and three-dimensional (3D)), and matrix density of 3D collagen...

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PMID: 32812979
DOI: 10.1039/d0bm01141j

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