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Article

The Human Mesenchymal Stromal Cell-Derived Osteocyte Capacity to Modulate Dendritic Cell Functions Is Strictly Dependent on the Culture System.

Journal of immunology research - 1 Jan 2015

Trabanelli Sara, La Manna Federico, Romano Marco, Salvestrini Valentina, Cavo Michele, Ciciarello Marilena, Lemoli Roberto M, Curti Antonio

Abstract excerpt

In vitro differentiation of mesenchymal stromal cells (MSC) into osteocytes (human differentiated osteogenic cells, hDOC) before implantation has been proposed to optimize bone regeneration. However, a deep characterization of the immunological properties of DOC, including their effect on dendritic cell (DC) function, is not available. DOC can be used either as cellular suspension (detached, Det-DOC) or as...

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Identifiers

PMID: 26247040
DOI: 10.1155/2015/526195
PMCID: PMC4515297

Genes

MSC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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