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Article

Immune interactions with CD4+ T cells promote the development of functional osteoclasts from murine CD11c+ dendritic cells.

Journal of immunology (Baltimore, Md. : 1950) - 1 Sept 2006

Alnaeeli Mawadda, Penninger Josef M, Teng Yen-Tung Andy

Abstract excerpt

Dendritic cells (DC) are innate immune effectors and are critically involved in regulating T cell immunity. Osteoclasts (OC) are bone-resorbing cells derived from the monocyte/macrophage lineage in response to receptor activator of NF-kappaB ligand (RANKL). DC and T cells form aggregates in the inflammatory infiltrates at active disease sites in human and in experimental rheumatoid arthritis and periodontitis. We...

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Identifiers

PMID: 16920972
DOI: 10.4049/jimmunol.177.5.3314

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Immune interactions with CD4+ T cells promote the development of functional osteoclasts from murine CD11c+ dendritic cells.PMID 16920972Read ↗

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