Article
Induction of p38, tumour necrosis factor-α and RANTES by mechanical stretching of keratinocytes expressing mutant keratin 10R156H.
The British journal of dermatology - 1 Jan 2011
Obarzanek-Fojt M, Favre B, Huber M, Ryser S, Moodycliffe A M, Wipff P-J, Hinz B, Hohl D
Abstract excerpt
BACKGROUND: Epidermolytic hyperkeratosis (bullous congenital ichthyosiform erythroderma), characterized by ichthyotic, rippled hyperkeratosis, erythroderma and skin blistering, is a rare autosomal dominant disease caused by mutations in keratin 1 or keratin 10 (K10) genes. A severe phenotype is c...
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