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Article

Keratins as an Inflammation Trigger Point in Epidermolysis Bullosa Simplex.

International journal of molecular sciences - 18 Nov 2021

Evtushenko Nadezhda A, Beilin Arkadii K, Kosykh Anastasiya V, Vorotelyak Ekaterina A, Gurskaya Nadya G

Abstract excerpt

Epidermolysis bullosa simplex (EBS) is a group of inherited keratinopathies that, in most cases, arise due to mutations in keratins and lead to intraepidermal ruptures. The cellular pathology of most EBS subtypes is associated with the fragility of the intermediate filament network, cytolysis of the basal layer of the epidermis, or attenuation of hemidesmosomal/desmosomal components. Mutations in keratins 5/14 or...

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Identifiers

PMID: 34830328
DOI: 10.3390/ijms222212446
PMCID: PMC8624175

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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