Article
Polymorphic variants of the CASP3, CASP9, BCL-2 and NKX3-1 genes as candidate markers for prostate cancer susceptibility and poor prognosis.
Molecular biology reports - 1 Sept 2022
de Souza Milene Roldão, de Souza Marilesia Ferreira, de Nóbrega Monyse, Cilião Heloísa Lizotti, Dos Reis Mariana Bisarro, Fuganti Paulo Emílio, Cólus Ilce Mara de Syllos
Abstract excerpt
BACKGROUND: There is an ongoing search for molecular markers that are specific, sensitive, and able to predict the stage of prostate cancer (PCa), which is the second most prevalent type of cancer in men worldwide. This study examined whether different single nucleotide polymorphisms (SNPs) were reliable markers of susceptibility to and prognosis of PCa in a sample of Brazilian patients. METHODS AND RESULTS: DNA...
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