Article
Association between single-nucleotide polymorphisms in Mal/TIRAP and interleukin-10 genes and susceptibility to invasive haemophilus influenzae serotype b infection in immunized children.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 1 Oct 2010
Ladhani Shamez N, Davila Sonia, Hibberd Martin L, Heath Paul T, Ramsay Mary E, Slack Mary P E, Pollard Andrew J, Booy Robert
Abstract excerpt
BACKGROUND: The development of invasive Haemophilus influenzae serotype b (Hib) disease after prior immunization with the Hib conjugate vaccine (ie, Hib vaccine failure) is extremely rare, suggesting that affected children may have an underlying genetic susceptibility in their immune response. Th...
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