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Article

Four and a half LIM protein 2 (FHL2) negatively regulates the transcription of E-cadherin through interaction with Snail1.

European journal of cancer (Oxford, England : 1990) - 1 Jan 2011

Zhang Wenjing, Wang Jide, Zou Bing, Sardet Claude, Li Jianming, Lam Colin S C, Ng Lui, Pang Roberta, Hung Ivan F N, Tan Victoria P Y, Jiang Bo, Wong Benjamin C Y

Abstract excerpt

E-cadherin is a hallmark of epithelial-mesenchymal transition (EMT), which plays a crucial role in cancer metastasis. We previously demonstrated that four and a half LIM protein 2 (FHL2) inhibited E-cadherin expression and promoted invasive potential and EMT in colon cancer. Here, we aim to furth...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20801642
DOI: 10.1016/j.ejca.2010.07.045

Genes

FHL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20801642-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Four and a half LIM protein 2 (FHL2) negatively regulates the transcription of E-cadherin through interaction with Snail1.PMID 20801642Read ↗

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