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Article

KLF8 promotes tumorigenesis, invasion and metastasis of colorectal cancer cells by transcriptional activation of FHL2.

Oncotarget - 22 Sept 2015

Yan Qingqing, Zhang Wenjing, Wu Yao, Wu Meiyan, Zhang Mengnan, Shi Xinpeng, Zhao Jinjun, Nan Qingzhen, Chen Ye, Wang Long, Cheng Tianming, Li Jiachu, Bai Yang, Liu Side, Wang Jide

Abstract excerpt

The transcription factor Krüppel-like factor (KLF)8 plays an important role in the formation of several human tumors, including colorectal cancer. We recently identified four-and-a-half LIM protein 2 (FHL2) as a critical inducer of the epithelial-to-mesenchymal transition (EMT) and invasion. Howe...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 26320172
DOI: 10.18632/oncotarget.4517
PMCID: PMC4694840

Genes

KLF8
FHL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-26320172-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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KLF8 promotes tumorigenesis, invasion and metastasis of colorectal cancer cells by transcriptional activation of FHL2.PMID 26320172Read ↗

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