Article
Association analysis between polymorphisms in the myo-inositol monophosphatase 2 (IMPA2) gene and bipolar disorder.
Progress in neuro-psychopharmacology & biological psychiatry - 1 Dec 2010
Bloch Paul J, Weller Andrew E, Doyle Glenn A, Ferraro Thomas N, Berrettini Wade H, Hodge Rachel, Lohoff Falk W
Abstract excerpt
Linkage studies in bipolar disorder (BPD) suggest that a susceptibility locus exists on chromosome 18p11. The myo-inositol monophosphatase 2 gene (IMPA2) maps to this genomic region. Myo-inositol monophosphatase dephosphorylates inositol monophosphate, regenerating free inositol. Lithium, a commo...
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