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Article

Examination of IMPA1 and IMPA2 genes in manic-depressive patients: association between IMPA2 promoter polymorphisms and bipolar disorder.

Molecular psychiatry - 1 Jun 2004

Sjøholt G, Ebstein R P, Lie R T, Berle J Ø, Mallet J, Deleuze J F, Levinson D F, Laurent C, Mujahed M, Bannoura I, Murad I, Molven A, Steen V M

Abstract excerpt

Manic-depressive (bipolar) illness is a serious psychiatric disorder with a strong genetic predisposition. The disorder is likely to be multifactorial and etiologically complex, and the causes of genetic susceptibility have been difficult to unveil. Lithium therapy is a widely used pharmacological treatment of manic-depressive illness, which both stabilizes the ongoing episodes and prevents relapses. A putative...

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Source

Identifiers

PMID: 14699425
DOI: 10.1038/sj.mp.4001460

Genes

IMPA2
IMPA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Examination of IMPA1 and IMPA2 genes in manic-depressive patients: association between IMPA2 promoter polymorphisms and bipolar disorder.PMID 14699425Read ↗

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