Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic association of cyclic AMP signaling genes with bipolar disorder.

Translational psychiatry - 2 Oct 2012

McDonald M L, MacMullen C, Liu D J, Leal S M, Davis R L

Abstract excerpt

The genetic basis for bipolar disorder (BPD) is complex with the involvement of multiple genes. As it is well established that cyclic adenosine monophosphate (cAMP) signaling regulates behavior, we tested variants in 29 genes that encode components of this signaling pathway for associations with BPD type I (BPD I) and BPD type II (BPD II). A total of 1172 individuals with BPD I, 516 individuals with BPD II and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bipolar Disorder
Share to Chromosome Mapping
Share to Cyclic AMP

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Haplotypes

Share to Linkage Disequilibrium

Share to Polymorphism, Single Nucleotide

Share to Signal Transduction

Source

Open in PubMed Open full text

Identifiers

PMID: 23032945
DOI: 10.1038/tp.2012.92
PMCID: PMC3565822

Genes

DISC1
GNAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic association of cyclic AMP signaling genes with bipolar disorder.PMID 23032945Read ↗

Analysis of genome-wide significant bipolar disorder genes in borderline personality disorderSemantic proximity Read ↗

Genetics of bipolar disorder.Semantic proximity Read ↗

High-resolution chromosome ideogram representation of recognized genes for bipolar disorder.Semantic proximity Read ↗

Genes Involved in Neurodevelopment, Neuroplasticity, and Bipolar Disorder: CACNA1C, CHRNA1, and MAPK1.Semantic proximity Read ↗

Association analysis of SCN9A gene variants with borderline personality disorder.Semantic proximity Read ↗

Past, present, and future of genetic research in borderline personality disorder.Semantic proximity Read ↗

Identification of novel loci for bipolar I disorder in a multi-stage genome-wide association study.Semantic proximity Read ↗

Searching high and low: a review of the genetics of bipolar disorderSemantic proximity Read ↗

Genome-wide association analyses of borderline personality disorder identify 11 loci and highlight shared risk with mental and somatic disorders.Semantic proximity Read ↗

Genome-wide association study of borderline personality disorder identifies 11 loci and highlights shared risk with mental and somatic disordersSemantic proximity Read ↗

Pathway analysis using information from allele-specific gene methylation in genome-wide association studies for bipolar disorder.Semantic proximity Read ↗

The genetics of bipolar disorder.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.