Article
Mutational analysis of the carboxy-terminal casein kinase II phosphorylation site in human c-myc.
Current topics in microbiology and immunology - 1 Jan 1990
Street A J, Blackwood E, Lüscher B, Eisenman R N
Abstract excerpt
Myc proteins are phosphorylated within two critical regions by casein kinase II (CKII): the central acidic domain and a carboxy-terminal region bordering the basic region-helix-loop-helix segment. In order to test whether the carboxy-terminal phosphorylation site was functionally important we introduced three types of mutations into this region. Two of the mutations would be expected to prevent phosphorylation...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
