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Article

Collagen mutation causes changes of the microdamage morphology in bone of an OI mouse model.

Bone - 1 Dec 2010

Dong X Neil, Zoghi Mahyar, Ran Qitao, Wang Xiaodu

Abstract excerpt

Previous studies have postulated that ultrastructural changes may alter the pattern and capacity of microdamage accumulation in bone. Using an osteogenesis imperfecta (OI) mouse model, this study was performed to investigate the correlation of collagen mutation with the microdamage morphology and the associated brittleness of bone. In this study, femurs from mild OI and wild type mice were fatigued under...

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Identifiers

PMID: 20736092
DOI: 10.1016/j.bone.2010.08.013
PMCID: PMC2970676

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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