Article
A haplotype inference algorithm for trios based on deterministic sampling.
BMC genetics - 23 Aug 2010
Iliadis Alexandros, Watkinson John, Anastassiou Dimitris, Wang Xiaodong
Abstract excerpt
BACKGROUND: In genome-wide association studies, thousands of individuals are genotyped in hundreds of thousands of single nucleotide polymorphisms (SNPs). Statistical power can be increased when haplotypes, rather than three-valued genotypes, are used in analysis, so the problem of haplotype phase inference (phasing) is particularly relevant. Several phasing algorithms have been developed for data from unrelated...
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