Article
2SNP: scalable phasing method for trios and unrelated individuals.
IEEE/ACM transactions on computational biology and bioinformatics - 1 Jan 2000
Brinza Dumitru, Zelikovsky Alexander
Abstract excerpt
Emerging microarray technologies allow affordable typing of very long genome sequences. A key challenge in analyzing of such huge amount of data is scalable and accurate computational inferring of haplotypes (i.e., splitting of each genotype into a pair of corresponding haplotypes). In this paper, we first phase genotypes consisting only of two SNPs using genotypes frequencies adjusted to the random mating model...
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