Article
Development of synthetic lethality in cancer: molecular and cellular classification.
Signal transduction and targeted therapy - 19 Oct 2020
Li Shijie, Topatana Win, Juengpanich Sarun, Cao Jiasheng, Hu Jiahao, Zhang Bin, Ma Diana, Cai Xiujun, Chen Mingyu
Abstract excerpt
Recently, genetically targeted cancer therapies have been a topic of great interest. Synthetic lethality provides a new approach for the treatment of mutated genes that were previously considered unable to be targeted in traditional genotype-targeted treatments. The increasing researches and applications in the clinical setting made synthetic lethality a promising anticancer treatment option. However, the current...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.