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Article

[Functional Bax polymorphism associated with lung cancer susceptibility].

Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 May 2010

Yu Dian-ke, Guo Yong-li, Tan Wen, Lin Dong-xin

Abstract excerpt

OBJECTIVE: The Bcl-2 associated X protein (Bax), belonging to the Bcl-2 family, plays a pivotal role in mitochondria-dependent apoptosis. The aims of this study are to revalidate the functional significance of Bax G(-248)A polymorphism, and investigate its association with lung cancer risk in Chinese population. METHODS: The biological function of Bax G(-248)A was tested by luciferase assays, and its effects on...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20723427

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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