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Article

BAX gene (-248 G > A) polymorphism in a sample of patients diagnosed with thyroid cancer in the Federal District, Brazil.

The International journal of biological markers - 1 Dec 2021

Cardoso-Duarte Ligia C A, Fratelli Caroline F, Pereira Alexandre S R, Souza Jéssica Nayane Gomes de, Freitas Renata de Souza, Morais Rafael Martins de, Sobrinho Alaor Barra, Sousa Silva Calliandra M, de Oliveira Jamila Reis, Oliveira Diêgo Madureira de, Silva Izabel Cristina R

Abstract excerpt

INTRODUCTION: Papillary thyroid cancer corresponds to approximately 1% of all carcinomas; nevertheless, it is the most prevalent endocrine neoplasm in the world. Studies reveal that the BAX (-248 G > A) polymorphism may be associated with negative regulation of BAX gene transcription activity, causing a decrease in its protein expression. OBJECTIVE: The present study aimed to describe the genotype and allele...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34825595
DOI: 10.1177/17246008211057576

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