Article
Association of a novel functional promoter variant (rs2075533 C>T) in the apoptosis gene TNFSF8 with risk of lung cancer--a finding from Texas lung cancer genome-wide association study.
Carcinogenesis - 1 Apr 2011
Wei Sheng, Niu Jiangong, Zhao Hui, Liu Zhensheng, Wang Li-E, Han Younghun, Chen Wei V, Amos Christopher I, Rafnar Thorunn, Sulem Patrick, Stefansson Kari, Landi Maria T, Caporaso Neil E, Albanes Demetrius, Thun Michael J, McKay James D, Brennan Paul, Wang Yufei, Houlston Richard S, Spitz Margaret R, Wei Qingyi
Abstract excerpt
Published genome-wide association studies (GWASs) have identified few variants in the known biological pathways involved in lung cancer etiology. To mine the possibly hidden causal single nucleotide polymorphisms (SNPs), we explored all SNPs in the extrinsic apoptosis pathway from our published G...
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