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Article

Amino acid substitutions in the FXYD motif enhance phospholemman-induced modulation of cardiac L-type calcium channels.

American journal of physiology. Cell physiology - 1 Nov 2010

Guo Kai, Wang Xianming, Gao Guofeng, Huang Congxin, Elmslie Keith S, Peterson Blaise Z

Abstract excerpt

We have found that phospholemman (PLM) associates with and modulates the gating of cardiac L-type calcium channels (Wang et al., Biophys J 98: 1149-1159, 2010). The short 17 amino acid extracellular NH(2)-terminal domain of PLM contains a highly conserved PFTYD sequence that defines it as a membe...

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Identifiers

PMID: 20720179
DOI: 10.1152/ajpcell.00149.2010
PMCID: PMC2980306

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20720179-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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