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Article

An evaluation of nine genetic variants related to metabolism and mechanism of action of warfarin as applied to stable dose prediction.

Journal of thrombosis and thrombolysis - 1 Oct 2010

Carlquist John F, Horne Benjamin D, Mower Chrissa, Park James, Huntinghouse John, McKinney Jason T, Muhlestein Joseph B, Anderson Jeffrey L

Abstract excerpt

Warfarin anticoagulation is complicated by the highly variable inter-individual response. Approximately 50% of the dose variability arises from clinical factors and variants in two genes, CYP2C9 (*2 and *3 variants) and VKORC1 -1173 C > T. We tested variants in five additional genes (EPHX1, PROC,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20499136
DOI: 10.1007/s11239-010-0467-3

Genes

VKORC1
APOE
CALU
EPHX1
PROC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20499136-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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