Association of cytochrome P450 1B1 (CYP1B1) polymorphism with steroid receptor status in breast cancer.

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Article

Association of cytochrome P450 1B1 (CYP1B1) polymorphism with steroid receptor status in breast cancer.

Cancer research - 15 Nov 1998

Bailey L R, Roodi N, Dupont W D, Parl F F

Abstract excerpt

A key enzyme involved in the production of potentially carcinogenic estrogen metabolites and the activation of environmental carcinogens is cytochrome P450 1B1 (CYP1B1), the predominant member of the CYP1 family expressed in normal breast tissue and breast cancer. Because of the preeminent role o...

Topics

Aryl Hydrocarbon Hydroxylases
Black People
Breast Neoplasms
Case-Control Studies
Cytochrome P-450 CYP1B1
Cytochrome P-450 Enzyme System
Estradiol
Exons
Female
Genotype
Humans
Polymorphism, Genetic
Receptors, Estrogen
Receptors, Progesterone
White People
Black or African American

Source

Open in PubMed

Identifiers

PMID: 9823305

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9823305-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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