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Association of cytochrome P450 1B1 (CYP1B1) polymorphism with steroid receptor status in breast cancer.

Cancer research - 15 Nov 1998

Bailey L R, Roodi N, Dupont W D, Parl F F

Abstract excerpt

A key enzyme involved in the production of potentially carcinogenic estrogen metabolites and the activation of environmental carcinogens is cytochrome P450 1B1 (CYP1B1), the predominant member of the CYP1 family expressed in normal breast tissue and breast cancer. Because of the preeminent role of CYP1B1 in mammary estrogen/carcinogen metabolism, we examined the CYP1B1 gene to determine whether genetic...

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PMID: 9823305

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Association of cytochrome P450 1B1 (CYP1B1) polymorphism with steroid receptor status in breast cancer.PMID 9823305Read ↗

No association between CYP1B1 Val432Leu polymorphism and breast cancer risk: a meta-analysis involving 40,303 subjects.Semantic proximity Read ↗

Association of CYP1B1 polymorphisms and breast cancer risk.Semantic proximity Read ↗

Lack of association of CYP1 B1*3 polymorphism and ovarian cancer in a Caucasian population.Semantic proximity Read ↗

Human CYP1B1 Leu432Val gene polymorphism: ethnic distribution in African-Americans, Caucasians and Chinese; oestradiol hydroxylase activity; and distribution in prostate cancer cases and controlsSemantic proximity Read ↗

Three polymorphisms in cytochrome P450 1B1 (CYP1B1) gene and breast cancer risk: a meta-analysis.Semantic proximity Read ↗

Association of CYP1B1 genetic polymorphism with incidence to breast and lung cancer.Semantic proximity Read ↗

African American-preponderant single nucleotide polymorphisms (SNPs) and risk of breast cancer.Semantic proximity Read ↗

Cytochrome P-450 1A1 gene polymorphisms and risk of breast cancer: a HuGE review.Semantic proximity Read ↗

Cytochrome P1B1 (CYP1B1) polymorphisms and ovarian cancer risk: a meta-analysis.Semantic proximity Read ↗

CYP1B1 and CYP19 gene polymorphisms and breast cancer incidence: no association in the ARIC study.Semantic proximity Read ↗

A variant in the cytochrome p450 oxidoreductase gene is associated with breast cancer risk in African Americans.Semantic proximity Read ↗

The Val432Leu polymorphism of the CYP1B1 gene is associated with differences in estrogen metabolism and bone density.Semantic proximity Read ↗

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