Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Bacteriophage Lysin Mediates the Binding of Streptococcus mitis to Human Platelets through Interaction with Fibrinogen

12 Aug 2010

Abstract excerpt

The binding of bacteria to human platelets is a likely central mechanism in the pathogenesis of infective endocarditis. We have previously found that platelet binding by Streptococcus mitis SF100 is mediated by surface components encoded by a lysogenic bacteriophage, SM1. We now demonstrate that SM1-encoded lysin contributes to platelet binding via its direct interaction with fibrinogen. Far Western blotting of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood groups and transfusion
Share to Infective Endocarditis Diagnosis and Management
Share to Streptococcal Infections and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20714354
DOI: 10.1371/journal.ppat.1001047

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bacteriophage Lysin Mediates the Binding of Streptococcus mitis to Human Platelets through Interaction with FibrinogenPMID 20714354Read ↗

Genetic loci of Streptococcus mitis that mediate binding to human platelets.Semantic proximity Read ↗

Proteins PblA and PblB of <i>Streptococcus mitis</i> , Which Promote Binding to Human Platelets, Are Encoded within a Lysogenic BacteriophageSemantic proximity Read ↗

Mechanism of cell surface expression of the Streptococcus mitis platelet binding proteins PblA and PblB.Semantic proximity Read ↗

Human fibrinogen bound to Streptococcus pyogenes M protein inhibits complement deposition via the classical pathwaySemantic proximity Read ↗

Distinct Serotypes of Streptococcal M Proteins Mediate Fibrinogen-Dependent Platelet Activation and Proinflammatory EffectsSemantic proximity Read ↗

A role for the fibrinogen-binding regions of streptococcal M proteins in phagocytosis resistance.Semantic proximity Read ↗

Binding of Glycoprotein Srr1 of Streptococcus agalactiae to Fibrinogen Promotes Attachment to Brain Endothelium and the Development of MeningitisSemantic proximity Read ↗

The Multifunctional <i>Staphylococcus aureus</i> Autolysin Aaa Mediates Adherence to Immobilized Fibrinogen and FibronectinSemantic proximity Read ↗

Potential involvement of Streptococcus mutans possessing collagen binding protein Cnm in infective endocarditisSemantic proximity Read ↗

Cytotoxic property of Streptococcus mitis strain producing two different types of cholesterol-dependent cytolysins.Semantic proximity Read ↗

Role of the Serine-Rich Surface Glycoprotein Srr1 of Streptococcus agalactiae in the Pathogenesis of Infective EndocarditisSemantic proximity Read ↗

A fibrinogen receptor from group B Streptococcus interacts with fibrinogen by repetitive units with novel ligand binding sitesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.