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Article

Genetic loci of Streptococcus mitis that mediate binding to human platelets.

Infection and immunity - 1 Mar 2001

Bensing B A, Rubens C E, Sullam P M

Abstract excerpt

The direct binding of bacteria to platelets is a postulated major interaction in the pathogenesis of infective endocarditis. To identify bacterial components that mediate platelet binding by Streptococcus mitis, we screened a Tn916deltaE-derived mutant library of S. mitis strain SF100 for reduced binding to human platelets in vitro. Two distinct loci were found to affect platelet binding. The first contains a...

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Share to Bacterial Adhesion
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 11179301
DOI: 10.1128/IAI.69.3.1373-1380.2001
PMCID: PMC98030

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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