Article
Proteins PblA and PblB of <i>Streptococcus mitis</i> , Which Promote Binding to Human Platelets, Are Encoded within a Lysogenic Bacteriophage
1 Oct 2001
Abstract excerpt
The binding of platelets by bacteria is a proposed central mechanism in the pathogenesis of infective endocarditis. Platelet binding by Streptococcus mitis strain SF100 (an endocarditis isolate) was recently shown to be mediated in part by the surface proteins PblA and PblB. The genes encoding PblA and PblB are clustered with genes nearly identical to those of streptococcal phages r1t, 01205, and Dp-1, suggesting...
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