The Multifunctional <i>Staphylococcus aureus</i> Autolysin Aaa Mediates Adherence to Immobilized Fibrinogen and Fibronectin

Abstract excerpt

Staphylococci can cause a wide spectrum of infections, including endocarditis, osteomyelitis, and sepsis, which is reflected by the numerous virulence factors they produce, among them a recently identified new class of adhesins, namely, the multifunctional autolysins/adhesins. Here we report the identification and molecular characterization of Aaa, a novel autolysin/adhesin from Staphylococcus aureus. The gene...

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