Article
Interleukin-1 receptor antagonist gene VNTR polymorphism is associated with coronary artery disease.
Arquivos brasileiros de cardiologia - 1 Nov 2008
Arman Ahmet, Soylu Ozer, Yildirim Ahmet, Furman Andrzej, Ercelen Nesrin, Aydogan Hakki, Coker Ajda, Tezel Tuna
Abstract excerpt
BACKGROUND: Coronary Artery Disease (CAD) is the atherosclerosis of coronary arteries that carry blood to the heart muscle. Atherosclerosis is an inflammatory disease. Cytokine gene variations such as those associated with the IL1 family are involved in the pathogenesis of atherosclerosis. OBJECTIVE: The purpose of this study was to determine the relationship between IL1 family polymorphisms (IL1RN VNTR, IL1B...
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