Article
Circulating interleukins in relation to coronary artery disease, atrial fibrillation and ischemic stroke and its subtypes: A two-sample Mendelian randomization study.
International journal of cardiology - 15 Aug 2020
Yuan Shuai, Lin Ang, He Qi-Qiang, Burgess Stephen, Larsson Susanna C
Abstract excerpt
BACKGROUND: The causal role of interleukins (ILs) for cardiovascular disease has not been fully elucidated. We conducted a Mendelian randomization study to investigate the associations of circulating ILs with coronary artery disease (CAD), atrial fibrillation (AF), and ischemic stroke. METHODS AND RESULTS: Single-nucleotide polymorphisms associated with IL-1β, IL-1 receptor antagonist (IL-1ra), IL-2 receptor...
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