Article
Association of interleukin 1 gene cluster and interleukin 1 receptor gene polymorphisms with ischemic heart failure.
Bratislavske lekarske listy - 1 Jan 2000
Mahmoudi M J, Taghvaei M, Harsini S, Amirzargar A A, Hedayat M, Mahmoudi M, Nematipour E, Farhadi E, Esfahanian N, Sadr M, Nourijelyani K, Rezaei N
Abstract excerpt
BACKGROUND: Proinflammatory cytokines have been known to play a considerable part in the pathomechanisms of chronic heart failure (CHF). Given the importance of proinflammatory cytokines in the context of the failing heart, we assessed whether the polymorphisms of interleukin (IL)-1 gene cluster, including IL-1α, IL-1β, and IL-1 receptor antagonist (IL-1RA) and IL-1R gene are predictors of CHF due to ischemic...
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