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Article

Ribozyme-mediated compensatory induction of menin-oncosuppressor function in primary fibroblasts from MEN1 patients.

Cancer gene therapy - 1 Nov 2010

Luzi E, Marini F, Tognarini I, Carbonell Sala S, Galli G, Falchetti A, Brandi M L

Abstract excerpt

Multiple endocrine neoplasia type 1 (MEN1) syndrome is characterized by the occurrence of tumors of parathyroids, neuroendocrine cells of the gastro-enteropancreatic tract and anterior pituitary. MEN1 gene encodes menin-oncosuppressor protein. Loss of heterozygosity at 11q13 is typical of MEN1 tu...

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Source

Identifiers

PMID: 20706287
DOI: 10.1038/cgt.2010.39

Genes

MEN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20706287-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Ribozyme-mediated compensatory induction of menin-oncosuppressor function in primary fibroblasts from MEN1 patients.PMID 20706287Read ↗

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Tumor Suppressor Menin Regulates Expression of Insulin-Like Growth Factor Binding Protein 2Semantic proximity Read ↗

Twenty years of menin: emerging opportunities for restoration of transcriptional regulation in MEN1Semantic proximity Read ↗

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Genetic ablation of the tumor suppressor menin causes lethality at mid-gestation with defects in multiple organs.Semantic proximity Read ↗

A novel splicing mutation (894-9 G --> A) of the MEN1 gene responsible for multiple endocrine neoplasia type 1.Semantic proximity Read ↗

The multiple endocrine neoplasia type 1 gene product, menin, inhibits the human prolactin promoter activitySemantic proximity Read ↗

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