Article
Expression analysis of endogenous menin, the product of the multiple endocrine neoplasia type 1 gene, in cell lines and human tissues.
International journal of cancer - 15 Mar 2000
Wautot V, Khodaei S, Frappart L, Buisson N, Baro E, Lenoir G M, Calender A, Zhang C X, Weber G
Abstract excerpt
We have investigated the endogenous expression of menin, a protein encoded by the gene mutated in multiple endocrine neoplasia type 1 (MEN1). Western blot analysis showed strong expression of menin as a 68 kDa protein in all of 7 human and primate cell lines tested. In a panel of 12 fetal human tissue extracts, 68 kDa menin was readily detected in brain cortex, kidney, pituitary, testis and thymus and weakly...
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