Article
Tyrosine hydroxylase polymorphism (C-824T) and hypertension: a population-based study.
American journal of hypertension - 1 Dec 2010
Nielsen Søren J, Jeppesen Jørgen, Torp-Pedersen Christian, Hansen Tine W, Linneberg Allan, Fenger Mogens
Abstract excerpt
BACKGROUND: Sympathetic nervous system (SNS) overactivity is present in a large proportion of the hypertensive population and precedes the development of established hypertension. Variations in the proximal promoter of the tyrosine hydroxylase (TH) gene have been shown to influence biochemical and physiological traits in the SNS as well as hypertension. METHODS: We investigated the relationship between a common...
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