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Article

Zyxin mediation of stretch-induced gene expression in human endothelial cells.

Circulation research - 1 Oct 2010

Wójtowicz Agnieszka, Babu Sahana Suresh, Li Li, Gretz Norbert, Hecker Markus, Cattaruzza Marco

Abstract excerpt

RATIONALE: Prolonged exposure to enhanced stretch, such as in hypertension, triggers endothelial dysfunction, a hallmark of pathological vascular remodeling processes. Despite its clinical relevance, little is known about stretch-induced gene expression in endothelial cells. OBJECTIVE: Here, we have characterized a new stretch-inducible signaling pathway and the subsequent changes in endothelial gene expression...

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Source

Identifiers

PMID: 20705921
DOI: 10.1161/CIRCRESAHA.110.227850

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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