Article
Clinical outcome of patients with follicular lymphoma receiving chemoimmunotherapy in the PRIMA study is not affected by FCGR3A and FCGR2A polymorphisms.
Blood - 27 Sept 2012
Ghesquières Hervé, Cartron Guillaume, Seymour John Francis, Delfau-Larue Marie-Hélène, Offner Fritz, Soubeyran Pierre, Perrot Aurore, Brice Pauline, Bouabdallah Réda, Sonet Anne, Dupuis Jehan, Casasnovas Olivier, Catalano John Vincent, Delmer Alain, Jardin Fabrice, Verney Aurélie, Dartigues Peggy, Salles Gilles
Abstract excerpt
In patients with follicular lymphoma treated with single-agent rituximab, single nucleotide polymorphisms in the FCGR3A gene are known to influence response and progression-free survival. The prognostic role of FCGR3A and FCGR2A polymorphisms in patients with follicular lymphoma treated with rituximab and chemotherapy combination remains controversial and has not been evaluated in the context of rituximab...
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