Article
Association analysis of GRM2 and HTR2A with methamphetamine-induced psychosis and schizophrenia in the Japanese population.
Progress in neuro-psychopharmacology & biological psychiatry - 30 May 2010
Tsunoka Tomoko, Kishi Taro, Kitajima Tsuyoshi, Okochi Tomo, Okumura Takenori, Yamanouchi Yoshio, Kinoshita Yoko, Kawashima Kunihiro, Naitoh Hiroshi, Inada Toshiya, Ujike Hiroshi, Yamada Mitsuhiko, Uchimura Naohisa, Sora Ichiro, Iyo Masaomi, Ozaki Norio, Iwata Nakao
Abstract excerpt
BACKGROUND: Abnormalities in glutaminergic neural transmission have been suggested to be involved in the pathogenesis of schizophrenia. A recent study reported that alterations in the 5-HT2A-mGluR2 complex may be involved in neural transmission in the schizophrenic cortex. In addition, methamphetamine-induced psychosis is thought to be similar to schizophrenia. Therefore, we conducted a case-control study with...
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