Article
Cdk phosphorylation of a nucleoporin controls localization of active genes through the cell cycle.
Molecular biology of the cell - 1 Oct 2010
Brickner Donna Garvey, Brickner Jason H
Abstract excerpt
Many inducible genes in yeast are targeted to the nuclear pore complex when active. We find that the peripheral localization of the INO1 and GAL1 genes is regulated through the cell cycle. Active INO1 and GAL1 localized at the nuclear periphery during G1, became nucleoplasmic during S-phase, and then returned to the nuclear periphery during G2/M. Loss of peripheral targeting followed the initiation of DNA...
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