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Article

Genetic regulation of mitotic competence in G 0 quiescent cells

3 Aug 2018

Abstract excerpt

cells must recycle proteins and RNA, governed by anabolism, catabolism, transport, and availability of small molecules such as antioxidants. Protein phosphatases are also essential to maintain MC. In particular, Nem1-Spo7 protects the nucleus from autophagy by regulating Ned1, a lipin. These genes, designated GZE (G-Zero Essential) genes, reveal the landscape of genetic regulation of MC.

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PMID: 30116786
DOI: 10.1126/sciadv.aat5685

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