Article
Screening RAD51C nucleotide alterations in patients with a family history of breast and ovarian cancer.
Breast cancer research and treatment - 1 Dec 2010
Zheng Yonglan, Zhang Jing, Hope Kisha, Niu Qun, Huo Dezheng, Olopade Olufunmilayo I
Abstract excerpt
It has been reported that one biallelic missense mutation in the RAD51C gene was found in a Fanconi anemia-like disorder and six monoallelic pathogenic mutations were identified in 480 BRCA1/2 negative breast and ovarian cancer pedigrees but not in 620 pedigrees with breast cancer only. Additiona...
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