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Article

Screening RAD51C nucleotide alterations in patients with a family history of breast and ovarian cancer.

Breast cancer research and treatment - 1 Dec 2010

Zheng Yonglan, Zhang Jing, Hope Kisha, Niu Qun, Huo Dezheng, Olopade Olufunmilayo I

Abstract excerpt

It has been reported that one biallelic missense mutation in the RAD51C gene was found in a Fanconi anemia-like disorder and six monoallelic pathogenic mutations were identified in 480 BRCA1/2 negative breast and ovarian cancer pedigrees but not in 620 pedigrees with breast cancer only. Additionally, the RAD51C gene was reported to be involved in gene fusion events in the MCF-7 breast cancer cell line. We...

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Identifiers

PMID: 20697805
DOI: 10.1007/s10549-010-1095-5

Genes

BRCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Screening RAD51C nucleotide alterations in patients with a family history of breast and ovarian cancer.PMID 20697805Read ↗

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Analysis of RAD51C germline mutations in high-risk breast and ovarian cancer families and ovarian cancer patientsSemantic proximity Read ↗

Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene.Semantic proximity Read ↗

RAD51C germline mutations in breast and ovarian cancer cases from high-risk families.Semantic proximity Read ↗

Further evidence for the contribution of the RAD51C gene in hereditary breast and ovarian cancer susceptibility.Semantic proximity Read ↗

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Analysis of RAD51C germline mutations in high-risk breast and ovarian cancer families and ovarian cancer patients.Semantic proximity Read ↗

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