Article
ETS family-associated gene fusions in Japanese prostate cancer: analysis of 194 radical prostatectomy samples.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Nov 2010
Miyagi Yohei, Sasaki Takeshi, Fujinami Kiyoshi, Sano Jinyu, Senga Yutaka, Miura Takeshi, Kameda Yoichi, Sakuma Yuji, Nakamura Yoshiyasu, Harada Masaoki, Tsuchiya Eiju
Abstract excerpt
The incidence and clinical significance of the TMPRSS2:ERG gene fusion in prostate cancer has been investigated with contradictory results. It is now common knowledge that significant variability in gene alterations exists according to ethnic background in various kinds of cancer. In this study, we evaluated gene fusions involving the ETS gene family in Japanese prostate cancer. Total RNA from 194 formalin-fixed...
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