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Article

SLUG/SNAI2 and tumor necrosis factor generate breast cells with CD44+/CD24- phenotype.

BMC cancer - 6 Aug 2010

Bhat-Nakshatri Poornima, Appaiah Hitesh, Ballas Christopher, Pick-Franke Patricia, Goulet Robert, Badve Sunil, Srour Edward F, Nakshatri Harikrishna

Abstract excerpt

BACKGROUND: Breast cancer cells with CD44+/CD24- cell surface marker expression profile are proposed as cancer stem cells (CSCs). Normal breast epithelial cells that are CD44+/CD24- express higher levels of stem/progenitor cell associated genes. We, amongst others, have shown that cancer cells that have undergone epithelial to mesenchymal transition (EMT) display the CD44+/CD24- phenotype. However, whether all...

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Identifiers

PMID: 20691079
DOI: 10.1186/1471-2407-10-411
PMCID: PMC3087321

Genes

TNF
SNAI2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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