Article
Recent translational research: stem cells as the roots of breast cancer.
Breast cancer research : BCR - 1 Jan 2006
Chang Chia-Cheng
Abstract excerpt
Common phenotypes of cancer and stem cells suggest that breast cancers arise from stem cells. Breast epithelial cells with stem cell phenotypes have been shown to be more susceptible to immortalization and neoplastic transformation. Breast tumor stem cells with CD44+/CD24-/lowLineage- markers have been isolated. The role of these cells in tumor progression and clinical outcome is not clear. The relationship...
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