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Role of an Expanded Inositol Transporter Repertoire in Cryptococcus neoformans Sexual Reproduction and Virulence

26 Mar 2010

Abstract excerpt

ABSTRACT Cryptococcus neoformans and Cryptococcus gattii are globally distributed human fungal pathogens and the leading causes of fungal meningitis. Recent studies reveal that myo -inositol is an important factor for fungal sexual reproduction. That C. neoformans can utilize myo -inositol as a sole carbon source and the existence of abundant inositol in the human central nervous system suggest that inositol is...

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PMID: 20689743
DOI: 10.1128/mbio.00084-10

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