Article
ROS receptor tyrosine kinase: a new potential target for anticancer drugs.
Medicinal research reviews - 1 Sept 2011
El-Deeb Ibrahim Mustafa, Yoo Kyung Ho, Lee So Ha
Abstract excerpt
ROS kinase is one of the last two remaining orphan receptor tyrosine kinases with an as yet unidentified ligand. The normal functions of human ROS kinase in different body tissues have not been fully identified so far. However, the ectopic expression, as well as the production of variable mutant forms of ROS kinase has been reported in a number of cancers, such as glioblastoma multiforme, and non-small cell lung...
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