Article
Quantitative and molecular genetic analyses of mutations increasing Drosophila life span.
PLoS genetics - 29 Jul 2010
Magwire Michael M, Yamamoto Akihiko, Carbone Mary Anna, Roshina Natalia V, Symonenko Alexander V, Pasyukova Elena G, Morozova Tatiana V, Mackay Trudy F C
Abstract excerpt
Understanding the genetic and environmental factors that affect variation in life span and senescence is of major interest for human health and evolutionary biology. Multiple mechanisms affect longevity, many of which are conserved across species, but the genetic networks underlying each mechanism and cross-talk between networks are unknown. We report the results of a screen for mutations affecting Drosophila...
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