Genetics of aging.

doi:10.1126/science.278.5337.407

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Article

Genetics of aging.

Science (New York, N.Y.) - 17 Oct 1997

Finch C E, Tanzi R E

Abstract excerpt

The role of genetics in determining life-span is complex and paradoxical. Although the heritability of life-span is relatively minor, some genetic variants significantly modify senescence of mammals and invertebrates, with both positive and negative impacts on age-related disorders and life-spans...

Topics

Aging
Alzheimer Disease
Animals
Apoptosis
Gene Expression
Genetic Variation
Humans
Longevity
Mutation
Risk Factors

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