Article
Genetic variation and aging.
Annual review of genetics - 1 Jan 1995
Curtsinger J W, Fukui H H, Khazaeli A A, Kirscher A, Pletcher S D, Promislow D E, Tatar M
Abstract excerpt
Life span is subject to genetic modification in yeasts, nematodes, fruit flies, mice, humans, and other vertebrates and invertebrates. There are a few single-gene mutants known that extend life span in yeast and nematodes; in other experimental systems the character is treated quantitatively, and generally has a low to moderate heritability. Life span responds to artificial selection in Drosophila and...
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